Michael reaction in synthesis of 6-amino-4-(4-butoxyphenyl)-3,5-dicyanopyridine-2(1H)-thione

Authors

  • B. Д. Дяченко T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011
  • B. П. Литвинов N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 117913

Abstract

The reaction of 4-butoxybenzalcyanoacetic ester with cyanothioacetamide yielded 6-amino-4-(4-butoxyphenyl)-3,5-dicyanopyridine-2(1H)-thione, also synthesized by recyclization of 2,6-diamino-4-(4-butoxyphenyl)-3,5-dicyano-4H-thiopyran and condensation of 4-butyoxybenzaldehyde with a two-fold excess of cyanothioacetamide. Substituted 2-alkylthiopyridines and thieno[2,3-b]pyridines were obtained with the indicated pyridinethione.

How to Cite
Kalvinsh, I.; Stradins, J.; Skorova, A.  Chem. Heterocycl. Compd. 1998, 34, 1. [Khim. Geterotsikl. Soedin. 1998, 34, 1.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02315182

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Published

1998-02-25

Issue

No. 2 (1998)

Section

Original Papers