Synthesis of N-acetyl derivatives of 5-and 6-ethoxy-2-methylthiobenzimidazole and their cardiotonic activity

Authors

  • А. Брyкштус Vilnius University, Vilnius LT-2006
  • А. Сиpвидитe Vilnius University, Vilnius LT-2006
  • В. Гараленe Vilnius University, Vilnius LT-2006
  • Л. Лабaнаускас Vilnius University, Vilnius LT-2006

Abstract

The regioselectivity of the N-acetylation of 5-and 6-ethoxy-2-methylthiobenzimidazole for various acetylating agents under various conditions has been investigated. The cardiotonic activity of the 1-acetyl-5-ethoxy-and 1-acetyl-6-ethoxy-2-methylthiobenzimidazoles synthesized and of their 5,6-diethoxy analog has been studied.

How to Cite
Brukshtus, A.; Sirvidite, A.; Garalene, V.; Labanauskas, L. Chem. Heterocycl. Compd. 1997, 33, 665. [Khim. Geterotsikl. Soedin. 1997, 765.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02291796

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Published

1997-06-25

Issue

No. 6 (1997)

Section

Original Papers