SYNTHЕSIS OF VARIОUS 5-(3-SUBSTITUTED PHENYL)-2'-DEOXYURIDINЕS

Authors

  • Ulf Wellmar Organic Chemistry I, Chemical Center, Box 124, 5-22100 Lund
  • Anna-Britta Hörnfeldt Organic Chemistry I, Chemical Center, Box 124, 5-22100 Lund
  • Salo Gronowitz Organic Chemistry I, Chemical Center, Box 124, 5-22100 Lund
  • Nils Gunnar Johansson Medivir AB, Liuiustigen. 7, 5-141 44 Huddinge

Abstract

A series of 5-aryl-2'-deoхуuridines has been prepared and evaluated as antiviral agents. The following substituents have been used in the position 3 of the phenyl ring: chloro, iodo, amino, azido , methylthio and vinyl . None of the new compounds showed any significant activity when tested against human immunodeficiency virus 1 (HIV-1), herpes
simplex virus 1 (HSV-1) or human cytomegalovirus (HCMV).

How to Cite
Wellmar, U.; Hörnfeldt, A.-B.; Gronowitz, S.; Gronowitz, S.; Johansson, N. G. Chem. Heterocycl. Compd. 1996, 32, 1312. [Khim. Geterotsikl. Soedin. 1996, 1528.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01169963

Downloads

Published

1996-11-25

Issue

No. 11/12 (1996)

Section

Original Papers