CYCLOCONDENSATION OF 2-PHENACYL-1H-BENZIMIDAZOLE WITH ACYLHYDRAZINES: SYNTHESIS AND TAUTOMERISM OF 2-(PYRAZOL-4-YL)-1H-BENZIMIDAZOLES

Authors

  • И. Б. Дзвинчук Institute of Organic Chemistry, Ukraine National Academy of Sciences
  • А. B. Выпирайленко Institute of Organic Chemistry, Ukraine National Academy of Sciences
  • B. B. Пироженко Institute of Organic Chemistry, Ukraine National Academy of Sciences
  • М. O. Лозинский Institute of Organic Chemistry, Ukraine National Academy of Sciences

DOI:

https://doi.org/10.1007/1071

Abstract

The previously unknown 2-(pyrazol-4-yl)benzimidazoles containing aryl groups in the pyrazolyl ring have been obtained by the reaction of 2-phenacyl-1H-benzimidazole with aroylhydrazines. The compounds with nitrophenyl and pyridyl substituents in the pyrazole ring show pyrazolyl tautomerism with differences in the 1H NMR spectra. A semi-empirical method is proposed to determine the tautomeric composition of the synthesized pyrazoles.

Authors: I. B. Dzvinchuk, A. V. Vypirailenko, V. V. Pirozhenko, and M. O. Lozinsky.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (11), pp 1319-1324

http://link.springer.com/article/10.1007/BF02252001

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Published

2013-10-29

Issue

No. 11 (1999)

Section

Original Papers