SYNTHESIS OF 3-CYANO-5-ETHOXYCARBONYL-4-METHYL-6-PHENYLPYRIDINE-2(1H)-THIONE AND ITS ALKYLATION

Authors

  • С. Г. Кpивокoлыско T. G. Shevchenko Lugansk State Pedagogical Institute
  • В. Д. Дяченко T. G. Shevchenko Lugansk State Pedagogical Institute
  • В. П. Литвинов N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

DOI:

https://doi.org/10.1007/1104

Abstract

The condensation of acetaldehyde with cyanothioacetamide and ethyl benzoylacetate in the presence of N-methylmorpholine leads to the formation of 3-cyano-5-ethoxycarbonyl-4-methyl-6-phenylpyridine-2(1H)-thione. Alkylation of the last afforded the corresponding substituted 2-alkylthiopyridines.

Authors: S. G. Krivokolysko, V. D. Dyachenko, and V. P. Litvinov.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (12), pp 1441-1442

http://link.springer.com/article/10.1007/BF02251819

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Published

2013-11-01

Issue

No. 12 (1999)

Section

Original Papers