Reactions of nitrophenylpyrimidines with benzyl cyanide. Synthesis of pyrimidinyl-2H-indazoles by the reductive cyclization of substituted dibenzoylazoxybenzenes

Abstract

The reaction of 2- and 5-(p-nitrophenyl)pyrimidines with benzyl cyanide in a strongly alkaline medium at 65°C gives pyrimidinyl derivatives of dibenzolyazoxybenzene. The conversion of these reagents is low at lower temperatures and a complex product mixture is obtained. The reduction of the azoxybenzene derivatives obtained leads to substituted 2H-indazoles.

How to Cite
Sedova, V. F.; Shkurko, O. P. Chem. Heterocycl. Compd. 1995, 31, 474. [Khim. Geterotsikl. Soedin. 1995, 540.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01177021