STUDY OF THE REACTIVITY OF SUBSTITUTED PHTHALIC ACIDS AND ANHYDRIDES IN CONDENSATION REACTIONS WITH N-CARBOXYMETHYLPYRIDINIUM SALTS AND THE SYNTHESIS OF NOVEL N-(1H-INDENE-1,3(2H)-DION-2-YL)PYRIDINIUM BETAINES

Abstract

Reaction of substituted phthalic acids or their anhydrides (including pyromellitic dianhydride) with salts of N-carboxymethylpyridinium and substituted N-carboxymethylpyridinium in the presence of acetic anhydride and triethylamine in acetonitrile or acetic acid solutions gave a series of novel N-(1H-indene-1,3(2H)-dion-2-yl)pyridinium betaines. Electron acceptor substituents in the phthaloyl and pyridine rings were found to increase and electron donor substituents – to decrease the reactivity.

Authors: O. Ya. Neilands, E. V. Shebenina, and G. G. Pukitis.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (12), pp 1443-1450

http://link.springer.com/article/10.1007/BF02251820