SYNTHESIS OF 2-ALKYLTHIO-SUBSTITUTED 4-OXO-3-<i>p</i>-TOLYL-3,4,5,6-TETRAHYDROSPIRO(BENZO[<i>h</i>]QUINAZOLINE-5,1'-CYCLOALKANES)
DOI:
https://doi.org/10.1007/1107Abstract
Reaction of 4-amino-3-carbethoxy-1,2-dihydrospiro(naphthalene-2,1'-cycloalkanes) with p-tolylisothiocyanate gave 4-oxo-2-thioxo-3-p-tolyl-1,2,3,4,5,6-hexahydro(benzo[h]quinazoline-5,1'-cycloalkanes) which could be alkylated using various halo compounds to yield the corresponding S-alkyl derivatives.
Authors: A. I. Markosyan, R. A. Kuroyan, and K. V. Karapetyan.
English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (12), pp 1451-1454