A SUITABLE SYNTHESIS OF [1,2,4]TRIAZOLO[4,3-<i>a</i>]PYRAZIN-8(7<i>H</i>)-ONE DERIVATIVES

Authors

  • S. S. Kovalenko National University of Pharmacy
  • K. Yu. Kulikovska National University of Pharmacy
  • O. G. Drushlyak National University of Pharmacy
  • I. O. Zhuravel National University of Pharmacy
  • S. M. Kovalenko National University of Pharmacy
  • V. P. Chernykh National University of Pharmacy

DOI:

https://doi.org/10.1007/1324

Keywords:

3-hydrazinopyrazin-2(1H)-one, orthoester, pyrazine-2, 3-dione, [1, 2, 4]triazolo[4, 3-a]pyrazin-8(7H)-one, cyclization

Abstract

A suitable approach to the synthesis of 3,7-disubstituted [1,2,4]triazolo[4,3-a]pyrazin-8(7H)-ones starting from esters of oxalic acid monoamides via cyclization of intermediate 3-hydrazinopyrazin-2-ones has been suggested.

How to Cite
Kovalenko, S. S.; Kulikovska, K. Yu.; Drushlyak, O. G.; Zhuravel, I. O.; Kovalenko, S. M.; Chernykh, V. P. Chem. Heterocycl. Compd. 2014, 50, 1147. [Khim. Geterotsikl. Soedin. 2014, 1243.]

For this article in the English edition see DOI 10.1007/s10593-014-1575-3

Author Biographies

S. S. Kovalenko, National University of Pharmacy

Svitlana Sergiyivna Kovalenko

K. Yu. Kulikovska, National University of Pharmacy

Kristina Yuriyivna Kulikovska

O. G. Drushlyak, National University of Pharmacy

Oleksandr Grigorievich Drushlyak

I. O. Zhuravel, National University of Pharmacy

Irina Oleksandrivna Zhuravel

S. M. Kovalenko, National University of Pharmacy

Sergiy Mykolayovich Kovalenko

V. P. Chernykh, National University of Pharmacy

Valentin Petrovich Chernykh

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Published

2014-08-26

Issue

No. 8 (2014)

Section

Original Papers