4-HYDROXY-2-QUINOLONES. 201. SYNTHESIS, STRUCTURE, AND DIURETIC ACTIVITY OF HYDROXY- AND ALKOXYANILIDES OF 6-HYDROXY-2-METHYL-4-OXO-2,4-DIHYDRO-1<i>H</i>-PYRROLO[3,2,1-<i>ij</i>]QUINOLINE-5-CARBOXYLIC ACID

Authors

  • И. В. Украинец National University of Pharmacy
  • Н. Ю. Голик National University of Pharmacy
  • А. Л. Шемчук National University of Pharmacy
  • В. Н. Кравченко National University of Pharmacy

DOI:

https://doi.org/10.1007/1395

Keywords:

anilides, 4-hydroxy-2-oxoquinoline-3-carboxylic acids, amidation, diuretic activity, X-ray structural analysis

Abstract

Hydroxy- and alkoxyanilides of 6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5 carboxylic acids have been synthesized as potential diuretic agents. Features of their purification, their steric structure, and biological activity are discussed.

Authors: I. V. Ukrainets, N. Yu. Golik, A. L. Shemchuk, and V. N. Kravchenko.

English translation in Chemistry of Heterocyclic Compounds, 2011, 47 (9), pp 1122-1127

http://link.springer.com/article/10.1007/s10593-011-0882-1

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Published

2013-12-17

Issue

No. 9 (2011)

Section

Original Papers