ULTRASOUND-ACCELERATED ONE-POT SYNTHESIS OF <i>N</i>-ACETYL-2-ARYL-1,2-DIHYDRO-4<i>H</i>-3,1-BENZOXAZIN-4-ONES

Abstract

The one-pot synthesis of N-acetyl-2-aryl-1,2-dihydro-4H-3,1-benzoxazin-4-one derivatives from the condensation reaction of anthranilic acids with heteroaromatic aldehydes in the presence of excess amount of acetic anhydride has been explored. The reactions proceed smoothly under ultrasound irradiation and without catalyst at 35−40°C to afford the title products in high yields.

Also published in Chemistry of Heterocyclic Compounds, 2011, 47 (9), pp 1128-1136

http://link.springer.com/article/10.1007/s10593-011-0883-0