THREE-COMPONENT CONDENSATION OF 2,5-DIALKYLPHENOLS, ISOBUTYRIC ALDEHYDE, AND NITRILES. SYNTHESIS OF NOVEL 2-AZASPIRO[4.5]DECA-6,9-DIEN- AND 2-AZASPIRO[4.5]DECA-1,6,9-TRIEN-8-ONES

Authors

  • Ю. С. Рожкова Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences
  • К. А. Галата Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences
  • Т. С. Вшивкова Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences
  • Ю. В. Шкляев Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences

DOI:

https://doi.org/10.1007/1472

Keywords:

2-azaspiro[4.5]deca-6, 9-dien-8-ones, 2-azaspiro[4.5]deca-1, 6, 9-trien-8-ones, 2-isopropyl-5-methylphenol, 2, 5-dimethylphenol, isobutyric aldehyde, nitrile, sulfuric acid, multicomponent reactions

Abstract

Interaction of 2,5-dialkylphenols (2,5-dimethylphenol and 2-isopropyl-5-methylphenol) with isobutyric aldehyde and nitriles catalyzed by concentrated sulfuric acid leads to the formation of 1-R-9-alkyl-3,3,6-trimethyl-2-azaspiro[4.5]deca-6,9-dien-8-ones and 1-R-9-alkyl-3,3,6-trimethyl-2-azaspiro[4.5]deca-1,6,9-trien-8-ones.

How to Cite
Rozhkova, Yu. S.; Galata, K. A.; Vshivkova, T. S.; Shklyaev, Yu. V. Chem. Heterocycl. Compd. 2014, 50, 204. [Khim. Geterotsikl. Soedin. 2014, 228.]

For this article in the English edition see DOI 10.1007/s10593-014-1462-y

Author Biographies

Ю. С. Рожкова, Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences

с.н.с. лаборатории синтеза активных реагентов

К. А. Галата, Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences

инженер лаборатории синтеза активных реагентов

Т. С. Вшивкова, Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences

н.с. лаборатории синтеза активных реагентов

Ю. В. Шкляев, Institute of Technical Chemistry, Ural Branch of the Russian Academy of Sciences

заведующий отделом органического синтеза

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Published

2014-02-13

Issue

No. 2 (2014)

Section

Original Papers