SYNTHESIS OF 3-(ALK-2-YN-1-YL)-1,3-OXAZOLIDINES USING COPPER-CONTAINING CATALYSTS
DOI:
https://doi.org/10.1007/1605Keywords:
3-(alk-2-yn-1-yl)-1, 3-oxazolidines, bis(1, 3-oxazolidin-3-yl)methane, 3, 8-dioxa-1, 6-diazabicyclo[4.4.1]undecane, terminal acetylenes, catalysisAbstract
A selective method for the synthesis of 3-(alk-2-yn-1-yl)-1,3-oxazolidines has been developed by the reaction of bis(oxazolidin-3-yl)methanes with terminal acetylenes with copper-containing catalysts. The reaction of terminal acetylenes with optically active bis((4R)-4-ethyl-1,3-oxazolidin-yl)methane led to the formation of (4R)-3-(2-alkynyl)-4-ethyl-1,3-oxazolidines.
How to Cite
Khabibullina, G. P.; Yanybin, V. M.; Ibragimov, A. G.; Dzhemilev, U. M. Chem. Heterocycl. Compd. 2014, 50, 726. [Khim. Geterotsikl. Soedin. 2014, 788.]
For this article in the English edition see DOI 10.1007/s10593-014-1527-y
