STUDIES IN THE 1,2,4-TRIAZOLE SERIES. III. AMINOMETHYLATION OF 4-PHENYL-1,2,4-TRIAZOLINETHIONE-3

Abstract

In a study of the aminomethylation of 4-phenyl-1,2,4-triazolinethione-3 (TRIT) it is ascertained that the reaction involves the nitrogen atom of the thioamide group. Salts of TRIT with secondary amines are obtained. It is shown that replacement of N (2) in 1-phenyltetrazolinethione-5 by the=CH- of TRIT leads to a decrease in the acidity of the thione and an increase in the stability of the hydroxymethyl and chloromethyl derivatives.

Authors: I. L. Shegal, I. Ya. Postovskii.

English Translation in Chemistry of Heterocyclic Compounds, 1965, 1 (1), pp 92-95

http://link.springer.com/article/10.1007/BF01168932