2,1-BENZOTHIAZINE 2,2-DIOXIDES. 8. SYNTHESIS AND STRUCTURE OF 2'-AMINO-2-OXO-1,2-DIHYDRO-6'<i>H</i>-SPIRO[INDOLE-3,4'-PYRANO[3,2-<i>c</i>][2,1]BENZOTHIAZINE]-3'-CARBONITRILE 5',5'-DIOXIDES
DOI:
https://doi.org/10.1007/1826Keywords:
4-oxo-3, 4-dihydro-1H-2λ6, 1-benzothiazine-2, 2-dioхide, isatin, malonodinitrile, pyrano[3, 2-c]benzothiazine, spiro[indole-3, 4'-pyran]Abstract
1-R-1H-2,1-benzothiazine-4(3H)-one 2,2-dioxides in the presence of triethylamine easily participate in three-component condensation with N-substituted isatines and malononitrile producing 1-R',6-R-2'-amino-2-oxo-1,2-dihydro-6'H-spiro[indole-3,4'-pyrano[3,2-c][2,1]benzothiazine]-3'-carbonitrile 5',5'-dioxides in good yields. The reaction with 1-R-1H-2,1-benzothiazine-4(3H)-one 2,2-dioxide not substituted in position 1 follows an analogous path, but its products are triethylammonium salts of the corresponding spiro compounds.
How to Cite
Ukrainets, I. V.; Petrushova, L. A.; Bereznyakova, N. L.; Liu Yangyang Chem. Heterocycl. Compd. 2014, 50, 1346. [Khim. Geterotsikl. Soedin. 2014, 1459.]
For this article in the English edition see DOI 10.1007/s10593-014-1598-9
