SYNTHESIS OF SUBSTITUTED 5<i>H</i>-1,2,3,4,6,7,8,9-OCTAHYDRODIPYRIDO[4,3-<i>b</i>;3',4'-<i>d</i>]PYRROLES BY THE PICTET–SPENGLER CONDENSATION
DOI:
https://doi.org/10.1007/207Keywords:
2, 5-bis(2-alkylaminoethyl)pyrroles, diazacarbazole, Pictet–Spengler reactionAbstract
N,N',N''-Trialkyl-2,5-bis(1-aminoethyl)pyrroles, prepared by the heterocyclization of 1,8-dibromooctan-3,6-dione with aliphatic amines, underwent the Pictet–Spengler reaction with formaldehyde and aromatic aldehydes to give substituted 5H-1,2,3,4,6,7,8,9-octahydrodipyrido[4,3-b;3',4'-d]pyrroles.
Authors: V. V. Bagutsky and O. G. Kulinkovich.
English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (5), pp 537-541
http://link.springer.com/article/10.1007/BF02290840