SYNTHESIS AND STRUCTURE OF A NEW HETEROCYCLIC SYSTEM – 7,8-DIHYDROIMIDAZO[1,2-<i>c</i>][1,3]THIAZOLO[4,5-<i>e</i>]PYRIMIDINE

Authors

  • А. П. Козаченко Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine
  • О. В. Шаблыкин Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine
  • А. Н. Василенко Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine
  • А. Н. Чернега Institute of Organic Chemistry, National Academy of Sciences of Ukraine
  • В. С. Броварец Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine

DOI:

https://doi.org/10.1007/2080

Keywords:

8-aroylamino-1, 2, 3, 7-tetrahydroimidazo[1, 2-c]pyrimidines, phosphorus pentasulfide, polyphosphoric acid, triethyl orthoformate, heterocyclization

Abstract

The purpose-directed synthesis of a new heterocyclic system, 7,8-dihydroimidazo[1,2-c][1,3]thiazolo[4,5-e]pyrimidine has been carried out based on the successive interaction of available 2-(aroylaminocyanomethylene) imidazolidines with hydrogen sulfide and triethyl orthoformate with subsequent intramolecular cyclocondensation of the obtained 8-aroylamino-7-thioxo-1,2,3,7-tetrahydroimidazo[1,2-c]pyrimidines under the action of phosphorus pentasulfide or polyphosphoric acid.

How to Cite
Kozachenko, A. P.; Shablykin, O. V.; Vasilenko, A. N.; Chernega, A. N.; Brovarets, V. S. Chem. Heterocycl. Compd. 2011, 47(4), 507. [Khim. Geterotsikl. Soedin. 2011, 613.]

For this article in the English edition see DOI 10.1007/s10593-011-0788-y

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Published

2014-11-28

Issue

No. 4 (2011)

Section

Original Papers