SYNTHESIS AND HETEROCYCLIZATION OF DITHIOCARBAMOYLACETOACETIC ESTERS AND ANILIDES

Abstract

The action of salts of N-monosubstituted dithiocarbamic acids on α-chloroacetoacetic ester and the corresponding anilide led to the isolation of the α-dithiocarbamoyl derivatives. These derivatives are converted, on standing or heating, to the ethyl ester and anilide of 4-methyl-3-methyl(aryl)-2-thiooxy-1,3-thiazolyl-5-carboxylic acids, which can be converted to the corresponding acid, acid chloride, and anilide.

Authors: V. V. Dovlatyan, K. A. Eliazyan, V. A. Pivazyan, E. A. Ghazaryan, A. P. Engoyan, R. T. Grigoryan, and R. G. Mirzoyan.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (5), pp 593-597

http://link.springer.com/article/10.1007/BF02290851