<i>E</i>-&beta;-STYRYLGERMATRANE

Abstract

E-β-1-(2-Phenylethenyl)-2,8,9-trioxa-5-aza-1-germatricyclo[3.3.3.0^1.5]undecane (β-styrylgermatrane) was obtained as the result of sequential reactions: the introduction of germanium dibromide at the C–Br bond of β-bromostyrene and the alcoholysis of tribromogermane to the triethoxy derivative with subsequent transetherification by triethanolamine. The structure of β-styrylgermatrane and 2.215 Å length of the transannular N→Ge bond were established by the method of NMR and X-ray diffraction analysis. It was found that the introduction of the CH=CH portion between the aromatic ring and the atrane grouping lowers the toxicity of the compound by the factor of 40.

Authors: L. Ignatovich, S. Belyakov, Yu. Popelis, and E. Lukevics.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (5), pp 603-606

http://link.springer.com/article/10.1007/BF02290853