AN EFFICIENT ONE-POT THREE-COMPONENT SYNTHESIS OF PYRIMIDO[4,5-<i>d</i>]PYRIMIDINE DERIVATIVES IN AQUEOUS MEDIUM
DOI:
https://doi.org/10.1007/2266Keywords:
6-amino-N, N-dimethyluracil, phenylisocyanate, phenylisothiocyanate, Lewis acid, PEG-bound sulfonic acid, threecomponent reactionAbstract
A fast, efficient, and green synthesis of pyrimido[4,5-d]pyrimidine derivatives has been achieved via one-pot three-component reaction starting from 6-amino-N,N-dimethyluracil, phenylisothiocyanate or phenylisocyanate, and aromatic aldehydes in the presence of polyethylene glycol-bound sulfonic acid as a catalyst in water as solvent.
How to Cite
Badvel, S.; Gopireddy, R. R.; Basha Shaik, T.; Hasti, S.; Tummaluru, V. R.; Chamarthi, N. R. Chem. Heterocycl. Compd. 2015, 51, 749. [Khim. Geterotsikl. Soedin. 2015, 51, 749.]
For this article in the English edition see DOI 10.1007/s10593-015-1769-3
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Published
2015-08-28
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Original Papers