SYNTHESIS OF 2-(PYRIDYLAZO)-2-FURYL- AND 2-(PYRIDYLAZO)-2-THIENYLMETHINES AND OTHER HETEROCYCLIC SCHIFF BASES IN THE PRESENCE OF MOLECULAR SIEVES

Abstract

The reactions of 2-furaldehyde, 2-thiophenecarbaldehyde, and their 5-methyl derivatives with 2‑aminopyridines and some other amines in the presence of molecular sieves as a dehydrating agent and acid catalyst have been studied. A series of new heterocyclic azomethines was synthesized. Proposals were made for the mechanism of the condensation involving 2-aminopyridines and the structure of the intermediates in these processes.

Authors: I. Iovel', L. Golomba, Yu. Popelis, S. Grinberga, and E. Lukevics.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (7), pp 779-786

http://link.springer.com/article/10.1007/BF02256909