BiCl<sub>3</sub> – AN ECO-FRIENDLY CATALYST FOR AN EFFICIENT SYNTHESIS OF BENZOXAZOLES AT ROOM TEMPERATURE

Authors

  • Vishvanath D. Patil University of Mumbai
  • Nagesh R. Sutar Organic Chemistry Research Laboratory, Department of Chemistry, C. K. Thakur A. C. S. College, New Panvel, Raigad, Maharashtra
  • Ketan P. Patil Organic Chemistry Research Laboratory, Department of Chemistry, C. K. Thakur A. C. S. College, New Panvel, Raigad, Maharashtra
  • Prathamesh V. Giddh Organic Chemistry Research Laboratory, Department of Chemistry, C. K. Thakur A. C. S. College, New Panvel, Raigad, Maharashtra

DOI:

https://doi.org/10.1007/2665

Keywords:

benzoxazole, bismuth trichloride, eco-friendly catalyst

Abstract

A simple and efficient protocol has been developed for the synthesis of 2-arylbenzoxazole derivatives of potential pharmaceutical interest. The method involves reaction between 2-aminophenol and substituted aromatic aldehydes in the presence of anhydrous bismuth trichloride as catalyst in acetonitrile. The use of eco-friendly bismuth trichloride, overall mild reaction conditions, and moderate to good yield of products are some attractive features of this methodology.

How to Cite
Patil, V. D.; Sutar, N. R.; Patil, K. P.; Giddh, P. Chem. Heterocycl. Compd. 2015, 51, 1019. [Khim. Geterotsikl. Soedin. 2015, 51, 1019.]

For this article in the English edition see DOI 10.1007/s10593-016-1814-x

Author Biographies

Vishvanath D. Patil, University of Mumbai

Assistant Professor, Department of Chemistry

Nagesh R. Sutar, Organic Chemistry Research Laboratory, Department of Chemistry, C. K. Thakur A. C. S. College, New Panvel, Raigad, Maharashtra

Assistant Professor, Department of Chemistry.

Ketan P. Patil, Organic Chemistry Research Laboratory, Department of Chemistry, C. K. Thakur A. C. S. College, New Panvel, Raigad, Maharashtra

Assistant Professor, Department of Chemistry.

Prathamesh V. Giddh, Organic Chemistry Research Laboratory, Department of Chemistry, C. K. Thakur A. C. S. College, New Panvel, Raigad, Maharashtra

Research Student, Department of Chemistry

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Published

2015-12-28

Issue

Vol. 51 No. 11/12 (2015)

Section

Original Papers