4(3H)-QUINAZOLINONES CONTAINING HETEROCYCLIC GROUP IN POSITION 3
DOI:
https://doi.org/10.1007/268Keywords:
2-methyl-3R-4(3H)-quinazolinones, 2-phenyl-3R-4(3H)-quinazolinones, 1, 2, 4-triazol-4-yl, 3-dimethyl-1-phenyl-5-pyrazolinon-4-yl, 3, 4-thiadiazol-2-yl, 3-cyano-6-phenyl-4-trifluoromethyl-2-pyridon-1-yl, 6, 6-dimethyl-4-oxo-4, 5, 7-tetrahydro-3-indazolylAbstract
The corresponding 2,3-substituted 4(3H)-quinazolinones were obtained in the reactions of 2-methyl- and 2-phenyl-4-oxo-3,1-benzoxazines with 1-amino-1,2,4-triazole, 4-amino-2,3-dimethyl-1-phenyl-5-pyrazolone, 2-amino-5-ethyl-1,3,4-thiadiazole, 3-amino-6,6-dimethyl-4-oxo-4,5,6,7-tetrahydroindazole, 1-amino-3-cyano-4,6-dimethyl-2-pyridone, and 1-amino-3-cyano-6-phenyl-4-trifluoromethyl-2-pyridone. The formation of N-benzoylanthranilamides in the reactions of 2-phenyl-4-oxo-3,1-benzoxazine with 2 amino-5-ethyl-1,3,4-thiadiazole and 1-amino-3-cyano-6-phenyl-4-trifluoromethyl-2-pyridones was exceptional. The structures of two of the products have been confirmed by X-ray crystallography.
Authors: N. N. Tonkikh, M. V. Petrova, A. F. Mishnev, K. V. Ryzhanova, F. M. Avotin'sh, and A. Ya. Strakov.
English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (7), pp 822-829
