ALKYLATION OF 5-ARYLTETRAZOLES WITH 2- AND 4-HYDROXYBENZYL ALCOHOLS
DOI:
https://doi.org/10.1007/2707Keywords:
5-aryltetrazoles, ortho-hydroxybenzyl alcohols, ortho-quinone methides, para-hydroxybenzyl alcohols, tetrazolylmethylphenols, aza-Michael reaction, hydroxybenzylationAbstract
The reaction of salicylic alcohol with 5-aryltetrazoles gave mixtures of 2-[(5-aryl-1H-tetrazol-1-yl)methyl]- and 2-[(5-aryl-2H-tetrazol-2yl)methyl]phenols. In the case of other ortho- and para-hydroxybenzyl alcohols, 2,5-disubstituted products were formed selectively. The criteria for detecting 1,5- and 2,5-disubstituted N-benzyltetrazoles by standard 1Н and 13С NMR spectroscopy have been identified.
How to Cite
Osyanin, V. A.; Osipov, D. V.; Nakushnov, V. Yu.; Zemtsova, M. N.; Klimochkin, Yu. N. Chem. Heterocycl. Compd. 2015, 51, 984. [Khim. Geterotsikl. Soedin. 2015, 51, 984.]
For this article in the English edition see DOI 10.1007/s10593-016-1808-8
