SYNTHESIS OF 5-TRIFLUOROMETHYLPYRAZOL-1-YL-SUBSTITUTED 1,2,4,5-TETRAZINES

Authors

  • С. Г. Толщина I. Ya. Postovskii Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences
  • Н. К. Игнатенко I. Ya. Postovskii Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences
  • П. А. Слепухин I. Ya. Postovskii Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences
  • Р. И. Ишметова I. Ya. Postovskii Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences
  • Г. Л. Русинов I. Ya. Postovskii Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences

DOI:

https://doi.org/10.1007/3040

Keywords:

5-hydroxy-5-trifluoromethylpyrazolines, 3, 6-di(3, 5-dimethylpyrazol-1-yl)-1, 2, 4, 5-tetrazine, 3-methyl-5-trifluoromethylpyrazole, 1, 5-tetrazines, triaminoguanidine, 1-trifluoro-2, 4-pentanedione

Abstract

Previously unknown products of the cyclocondensation of 1,1,1-trifluoro-2,4-pentanedione with triaminoguanidine and hydrazine derivatives of 1,2,4,5-tetrazine have been obtained. 5-Hydroxy-5-tri-fluoromethylpyrazoline substituents formed on the tetrazine ring were dehydrated under the action of trifluoroacetic anhydride. A comparison has been carried out of the reactivity of 5-trifluoro-methylpyrazolyl-substituted 1,2,4,5-tetrazines and their unfluorinated analogs in nucleophilic substitution and [4 + 2] cycloaddition reactions.

How to Cite
Tolshchina, S. G.; Ignatenko, N. K.; Slepukhin, P. A.; Ishmetova, R. I.; Rusinov, G. L. Chem. Heterocycl. Compd. 2010, 46, 691. [Khim. Geterotsikl. Soedin. 2010, 860.]

For this article in the English edition see DOI 10.1007/s10593-010-0571-5

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Published

2016-02-09

Issue

No. 6 (2010)

Section

Original Papers