SYNTHESIS AND ALKYLATION OF 4-ARYL-5-OXO-1<i>H</i>-2,3,4,5-TETRAHYDROINDENO[1,2-<i>b</i>]PYRIDINES

Authors

  • C. Cтупникова Latvian Institute of Organic Synthesis
  • Е. Петушкова Latvian Institute of Organic Synthesis
  • Д. Танаев Latvian Institute of Organic Synthesis
  • В. Лусис Latvian Institute of Organic Synthesis
  • Д. Муцениеце Latvian Institute of Organic Synthesis

DOI:

https://doi.org/10.1007/3082

Keywords:

5-oxo-4, 5-dihydro-1H- and 2, 3, 4, 5-tetrahydro-1H-indeno[1, 2-b]pyridines, N- and C(4a)-alkylation of 5-oxo-2, 2-b]pyridine, triethylsilane reduction

Abstract

Reduction of 5-oxo-4-phenyl-1H-4,5-dihydroindeno[1,2-b]pyridines with triethylsilane in trifluoroacetic acid gave the corresponding 1,2,3,4-tetrahydroindeno[1,2-b]pyridines predominatly with the trans-configured substituents at atoms C(2), C(3), and C(4). Alkylation of the anionic form of the tetrahydroindenopyridines gives the N- and C(4a)-alkyl derivatives.

How to Cite
Stupnikova, S.; Petushkova, E.; Tanajev, D.; Lusis, V.; Muceniece, D. Chem. Heterocycl. Compd. 2010, 46, 859. [Khim. Geterotsikl. Soedin. 2010, 1062.]

For this article in the English edition see DOI 10.1007/s10593-010-0595-x

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Published

2016-02-24

Issue

No. 7 (2010)

Section

Original Papers