4-HYDROXYQUINOLIN-2-ONES. 45. SYNTHESIS, STRUCTURE, AND BIOLOGICAL ACTIVITY OF N-SUBSTITUTED 1H-4-HYDROXY-2-OXOQUINOLINE-3-ACETIC ACID AMIDES

Authors

  • И. B. Украинец National Pharmaceutical Academy of the Ukraine
  • C. Г. Таран National Pharmaceutical Academy of the Ukraine
  • O. Л. Каменецкая National Pharmaceutical Academy of the Ukraine
  • O. B. Горохова National Pharmaceutical Academy of the Ukraine
  • Л. B. Сидоренко National Pharmaceutical Academy of the Ukraine
  • А. В. Туров Taras Shevchenko University

DOI:

https://doi.org/10.1007/435

Keywords:

amides, tetrahydrofuroquinoline, quinoline-3-acetic acid, X-ray diffraction analysis, thyroid-stimulating activity

Abstract

A preparative method is proposed for obtaining N-substituted 1H-4-hydroxy-2-oxoquinoline-3-acetic acid amides. X-Ray diffraction analysis of one of the synthesized compounds has been carried out. The effect of the obtained substances on thyroid gland function has been studied.

Authors: I. V. Ukrainets, S. G. Taran, O. L. Kamenetskaya, O. V. Gorokhova, L. V. Sidorenko, and A. V. Turov.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (11), pp 1319-1325

http://link.springer.com/article/10.1023/A%3A1017527702970

Downloads

Published

2013-03-27

Issue

No. 11 (2000)

Section

Original Papers