STABILIZED AZOMETHINE YLIDES DERIVED FROM INDENO[1,2-<i>b</i>]QUINOXALINONES IN [3+2] CYCLOADDITION REACTIONS WITH ELECTROPHILIC ALKENES

Authors

  • Владислав Юрьевич Коротаев Уральский федеральный университет
  • Николай Сергеевич Зимницкий Уральский федеральный университет
  • Игорь Борисович Кутяшев Уральский федеральный университет
  • Алексей Юрьевич Барков Уральский федеральный университет
  • Вячеслав Яковлевич Сосновских Уральский федеральный университет

DOI:

https://doi.org/10.1007/4673

Keywords:

6H-indeno[1, 2-b]pyrido[3, 2-e]pyrazin-6-one, 11H-indeno[1, 2-b]quinoxalin-11-one, electrophilic alkenes, stabilized azomethine ylides, biological activity, 1, 3-dipolar cycloaddition, multicomponent reactions

Abstract

We provide a general and systematic review of all currently published data on the use of stabilized azomethine ylides derived from 11H-indeno[1,2-b]quinoxalin-11-one and 6H-indeno[1,2-b]pyrido[3,2-e]pyrazin-6-one in the synthesis of spiropyrrolidines and spiropyrrolizidines. The reaction conditions, as well as the regio- and stereoselectivity of the [3+2] cycloaddition process are discussed. Data on the biological activity of the obtained products are presented. There are 62 literature references.

 

Authors: Vladislav Yu. Korotaev, Nikolay S. Zimnitskiy, Alexey Yu. Barkov,
Igor B. Kutyashev, Vyacheslav Ya. Sosnovskikh

 

 

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Published

2018-11-12

Issue

Vol. 54 No. 10 (2018)

Section

Review Articles