SYNTHESIS OF CHROMENO[2,3-<i>c</i>]PYRROL-9(2<i>H</i>)-ONES BY DOMINO REACTIONS OF AMINO ACIDS WITH YNONES

Authors

  • Mariia Miliutina Institut für Chemie, Universität Rostock, 3a Albert Einstein St., Rostock 18059, Germany
  • Yevhen Ivon
  • Evgeniy Y. Slobodyanyuk
  • Syeda Abida Ejaz
  • Jamshed Iqbal
  • Alexander Villinger
  • Viktor O. Iaroshenko
  • Peter Langer Institut für Chemie, Universität Rostock, 3a Albert Einstein St., Rostock 18059, Germany

DOI:

https://doi.org/10.1007/4940

Keywords:

amino acids, chromeno[2, 3-c]pyrrol-9(2H)-ones, heterocycles, alkaline phosphatase inhibitory activity, domino reactions.

Abstract

The synthesis of novel chromeno[2,3-c]pyrrol-9(2H)-ones via domino reaction of amino acids with aromatic α,β-ynones is described. Obtained chromeno[2,3-c]pyrrol-9(2H)-ones possess phosphatase inhibitory activity.

 

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Published

2019-05-22

Issue

Vol. 55 No. 4/5 (2019): In memory of Professor Valerii Dmitrievich Orlov

Section

Short Communications