RECENT APPROACHES TO THE SYNTHESIS OF 2<i>H</i>-AZIRINES

Authors

  • Nagarajan Ramkumar Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, Leuven B-3001
  • Leonid G. Voskressensky Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow 117198
  • Upendra K. Sharma Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, Leuven B-3001
  • Erik V. Van der Eycken Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, Leuven B-3001 Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow 117198

DOI:

https://doi.org/10.1007/5028

Keywords:

azaheterocycles, 2H-azirines, small-ring heterocycles

Abstract

The most recent (2013–2018) synthetic approaches toward 2H-azirine     derivatives are summarized and discussed. This minireview covers the latest examples on the synthesis of 2H-azirines that can be gathered in five distinct categories: the Neber approach, decomposition of vinyl azides, ring contraction of isoxazoles, oxidative cyclization of enamine derivatives, and radical addition/cyclization of alkynes.

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Published

2019-09-13

Issue

Vol. 55 No. 9 (2019)

Section

Review Articles