SYNTHESIS OF 2,5-DISUBSTITUTED 1,3,4-OXADIAZOLES CONTAINING BENZOTHIAZOLYLTHIOL GROUPING

Authors

  • В. И. Келарев I. M. Gubkin Russian State University for Petroleum and Gas, Moscow
  • М. А. Силин I. M. Gubkin Russian State University for Petroleum and Gas, Moscow
  • H. А. Григорьева I. M. Gubkin Russian State University for Petroleum and Gas, Moscow
  • B. H. Кошелев I. M. Gubkin Russian State University for Petroleum and Gas, Moscow

DOI:

https://doi.org/10.1007/55

Keywords:

benzothiazole, carboxylic acid hydrazides, carboxylic acid imino ester hydrochlorides, 2 mercaptobenzothiazole, 1, 3, 4-oxadiazole, condensation

Abstract

A series of 2,5-substituted 1,3,4-oxadiazoles containing 2-benzothiazolylthiomethyl grouping has been synthesized by condensing derivatives of (2-benzothiazolylthio)acetic acid with imino ester hydrochlorides and hydrazides of carboxylic acids, by the cyclodehydration of N-acyl-N'-(2-benzothiazolylthioacetyl)hydrazines under the action of POCl3, and also by the reaction of 2‑mercaptobenzothiazole with 2-chloromethyl-1,3,4-oxadiazoles in the presence of sodium methylate.

Authors: V. I. Kelarev, M. A. Silin, N. A. Grigor'eva, and V. N. Koshelev.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (2), pp 207-213

http://link.springer.com/article/10.1007/BF02283554

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Published

2012-11-16

Issue

No. 2 (2000)

Section

Original Papers