SYNTHESIS OF 2',3',4'-TRIARYL-5,6-DIHYDRO-8<i>H</i>-SPIRO[INDOLIZINE-7,5'-ISOXAZOLIDIN]-8-ONES <i>VIA</i> 1,3-DIPOLAR CYCLOADDITION REACTION INVOLVING (<i>Z</i>)-<i>C</i>-ARYL-<i>N</i>-PHENYLNITRONES
DOI:
https://doi.org/10.1007/5574Keywords:
indolizine, isoxazolidine, nitrone, 1, 3-dipolar cycloaddition.Abstract
The 1,3-dipolar cycloaddition of C-aryl-N-phenylnitrones to 7-arylmethylidene-6,7-dihydroindolizin-8(5H)-ones afforded novel 2',3',4'-triaryl-5,6-dihydro-8H-spiro[indolizine-7,5'-isoxazolidin]-8-ones in moderate yields. The structures of all the products were proved by NMR and IR spectroscopy, HRMS, and X-ray analysis.
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Published
2020-09-17
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Original Papers