2-YLIDENE-1,3-THIAZOLIDINES AND THEIR NONHYDROGENATED ANALOGS: METHODS OF SYNTHESIS AND CHEMICAL PROPERTIES

Authors

  • Мария Б. Литвинчук Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094
  • Антон В. Бентя Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094
  • Наталия Ю. Сливка Lesya Ukrainka Eastern European National University, 13 Voli Ave., Lutsk 43025
  • Михаил В. Вовк Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094

DOI:

https://doi.org/10.1007/5715

Keywords:

2-ylidene-1, 3-thiazolidines, 2-ylidene-2, 3-dihydro-1, 3-thiazoles, cyclocondensation, electrophilic cyclization, functionalization

Abstract

The review summarizes and systematizes the literature data on the methods of synthesis and chemical properties of 2-ylidene-1,3-thiazolidines and 2-ylidene-2,3-dihydro-1,3-thiazoles. Two general approaches to their preparation have been identified: the construction of the 2-ylidene-1,3-thiazolidine ring from acyclic precursors in one synthetic process and the introduction of the 2-ylidene fragment into the 1,3-thiazolidine ring. The main chemical transformations of 2-ylidene-1,3-thiazolidines and 2-ylidene-2,3-dihydro-1,3-thiazoles, which include the reactions of selective functionalization and heterocyclization at the ylidene fragment and thiazolidine backbone, are considered. The bibliography of the review consists of 97 references published from 2000 to 2020.

Authors: Mariia B. Litvinchuk*, Anton V. Bentya, Nataliia Yu. Slyvka, Mikhailo V. Vovk

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Published

2020-10-14

Issue

Vol. 56 No. 9 (2020)

Section

Review Articles