ALKYLATION OF HETARYL METHYL KETONES BY PROPARGYL BROMIDE UNDER PHASE-TRANSFER CATALYSIS CONDITIONS

Authors

  • Э. Абеле Latvian Institute of Organic Synthesis
  • P. Абеле Latvian Institute of Organic Synthesis
  • Ю. Попелис Latvian Institute of Organic Synthesis
  • И. Мажейка Latvian Institute of Organic Synthesis
  • Э. Лукевиц Latvian Institute of Organic Synthesis

DOI:

https://doi.org/10.1007/589

Abstract

The alkylation of aryl and hetaryl methyl ketones by propargyl bromide using the phase-transfer catalysis system KOH (s)/18-crown-6/benzene is studied. The corresponding C-trialkylated products are selectively obtained in 34-78% yields.

Authors: E. Abele, R. Abele, Yu. Popelis, I. Mazheika, and E. Lukevics.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (4), pp 436-438

http://link.springer.com/article/10.1007/BF02319330

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Published

2013-05-10

Issue

No. 4 (1999)

Section

Original Papers