MODELING THE BINDING OF PROTOPORPHYRIN IX, VERTEPORFIN, AND CHLORIN e6 TO SARS-CoV-2 PROTEINS

Authors

  • Оскар И. Койфман G. A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences, 1 Akademicheskaya St., Ivanovo 153045, Russia Ivanovo State University of Chemistry and Technology, 7 Sheremetevskii Ave., Ivanovo 153000, Russia
  • Наталья Ш. Лебедева G. A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences, 1 Akademicheskaya St., Ivanovo 153045, Russia Ivanovo State University of Chemistry and Technology, 7 Sheremetevskii Ave., Ivanovo 153000, Russia
  • Юрий А. Губарев G. A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences, 1 Akademicheskaya St., Ivanovo 153045, Russia
  • Михаил О. Койфман Ivanovo State University of Chemistry and Technology, 7 Sheremetevskii Ave., Ivanovo 153000, Russia

DOI:

https://doi.org/10.1007/6000

Keywords:

chlorin e6, porphyrins, protoporphyrin IX, verteporfin, COVID-19, molecular docking, SARS-CoV-2.

Abstract

In this work, we analyze the latest data on the molecular docking of a range of SARS-CoV-2 proteins to protoporphyrin IX, verteporfin, and chlorin e6, as well as consider the prospects for using chlorins and porphyrins as agents for photoinactivation of the SARS2 virus.

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Published

2021-05-05

Issue

Vol. 57 No. 4 (2021): Heterocycles Against Viruses

Section

Original Papers