Bu<sub>3</sub>P-MEDIATED ACYLATION OF (<i>E</i>)-7-ARYLIDENE-6,7-DIHYDROINDOLIZIN-8(5<i>H</i>)-ONES WITH ACYL CHLORIDES

Authors

  • Sha Li Key Laboratory of Theoretical Organic Chemistry and Functional Molecules, Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan Taoyuan Road, Hunan 411201, China
  • Jiaxi Tan Key Laboratory of Theoretical Organic Chemistry and Functional Molecules, Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan Taoyuan Road, Hunan 411201, China
  • Xiaofang Li Key Laboratory of Theoretical Organic Chemistry and Functional Molecules, Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan Taoyuan Road, Hunan 411201, China

DOI:

https://doi.org/10.1007/6111

Keywords:

acyl chlorides, indolizin-8(5H)-ones, tributylphosphine, acylation.

Abstract

The (Z)-7-(1,2-diaryl-2-oxoethylidene)-6,7-dihydroindolizin-8(5H)-ones were synthesized in the acylation reaction of (E)-7-arylidene-6,7-dihydroindolizin-8(5H)-ones with acyl chlorides in the presence of Bu3P in moderate yields. The structures of all products were characterized thoroughly by NMR, IR, HRMS together with X-ray crystallographic analysis.

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Published

2021-05-26

Issue

Vol. 57 No. 5 (2021)

Section

Original Papers