CYCLOCONDENSATION OF 5-CHLORO-4-FORMYLPYRROLE-3-CARBOXYLATES WITH ARYLAMINES. SYNTHESIS AND FLUORESCENT PROPERTIES OF PYRROLO[2,3-<i>b</i>]QUINOLINE-3-CARBOXYLATES AND THEIR BENZO[<i>f</i>] ANALOGS

Authors

  • Алина Н. Грозав Bukovinian State Medical University, 2 Teatral'na Sq., Chernivtsi 58000, Ukraine
  • Марьяна З. Федорив Ivano-Frankivsk National Medical University, 2 Galytska St., Ivano-Frankivsk 76018, Ukraine
  • Виталий А. Чорноус Bukovinian State Medical University, 2 Teatral'na Sq., Chernivtsi 58000, Ukraine
  • Сергей В. Кемский Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094, Ukraine
  • Владислав М. Полищук Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094, Ukraine
  • Николай П. Шандура Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094, Ukraine
  • Эдуард Б. Русанов Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094, Ukraine
  • Михаил В. Вовк Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02094, Ukraine

DOI:

https://doi.org/10.1007/6353

Keywords:

arylamines, benzo[f]pyrrolo[2, 3-b]quinoline-10-carboxylates, 3-b]quinoline-10-carboxylic acids, 5-chloro-4-formylpyrrole-3-carboxylates, pyrrolo[2, 3-b]quinoline-3-carboxylates, 3-b]quinoline-3-carboxylic acids, alkaline hydrolysis, cyclocondensation, fluorescent properties.

Abstract

5-Chloro-4-formylpyrrole-3-carboxylates react with anilines or β-naphthylamine when heated in DMF under reflux to form ethyl pyrrolo[2,3-b]quinoline-3-carboxylates or their benzo[f] analogs, which exhibit moderate fluorescent properties. The corresponding carboxylic acids were obtained by alkaline hydrolysis of the synthesized carboxylates.

 

Author Biography

Алина Н. Грозав, Bukovinian State Medical University, 2 Teatral'na Sq., Chernivtsi 58000, Ukraine

кандидат химических наук (органическая химия), доцент кафедры медицинской и фармацевтической химии

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Published

2021-10-21

Issue

Vol. 57 No. 10 (2021)

Section

Original Papers