REACTION OF 5-HYDROXY-3,3,5-TRIMETHYLISOXAZOLIDINE WITH ACRYLIC ACID ESTERS

Authors

  • А. Ю. Ершов Institute of High-Molecular Compounds, Russian Academy of Sciences
  • Н. В. Кошмина St. Petersburg State University
  • А. В. Добродумов Institute of High-Molecular Compounds, Russian Academy of Sciences

DOI:

https://doi.org/10.1007/693

Abstract

The reaction of 5-hydroxy-3,3,5-trimethylisoxazolidine with methyl, ethyl, and tert-butyl acrylates, proceeds as Michael addition, and produces previously unknown 5-hydroxy-3,3,5-trimethylisoxazolidine-2-propionic acid esters. The structures of the obtained products are proved by 1H and 13C NMR spectroscopy and by their subsequent transformation into 5-hydroxy-3,3,5-trimethylisoxazolidine-2-propionic acid.

Authors: A. Yu. Ershov, N. V. Koshmina, and A. V. Dobrodumov.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (7), pp 829-831

http://link.springer.com/article/10.1007/BF02252110

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Published

2013-06-06

Issue

No. 7 (1999)

Section

Original Papers