METHYL NITROACETATE AND 3-NITROPROPIONATE IN THE SYNTHESIS OF HEXAHYDROPYRIMIDINES AND PIPERIDINES
DOI:
https://doi.org/10.1007/6937Keywords:
hexahydropyrimidines, 3, 5-dinitropiperidines, methyl nitrocarboxylates, Mannich reactionAbstract
Treatment of methyl nitroacetate and 3-nitropropionate with formaldehyde and primary amines under Mannich reaction conditions gives 5-nitrohexahydropyrimidines. In the case of methyl nitroacetate both the 5-nitrohexahydropyrimidine and isomeric 3,5-di(methoxycarbonyl)-1-methyl-3,5-dinitropiperidines are formed.How to Cite
Shakirov, R. R.; Dokichev, T. V.; Biglova, R. Z.; Vlasova, N. M.;
Baibulatova, N. Z.; Talipov, R. F. Chem. Heterocycl. Compd. 2008, 44, 43. [Khim. Geterotsikl. Soedin. 2008, 53.]
For this article in the English edition see DOI 10.1007/s10593-008-0011-y