4-HYDROXY-2-QUINOLONES. 142. 4-METHYL-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLIC ACID ANILIDES AS POTENTIAL DIURETICS

Authors

  • И. В. Украинец National University of Pharmacy, Kharkiv 61002
  • Н. Л. Березнякова National University of Pharmacy, Kharkiv 61002
  • В. А. Паршиков National University of Pharmacy, Kharkiv 61002
  • О. И. Набока National University of Pharmacy, Kharkiv 61002

DOI:

https://doi.org/10.1007/6971

Keywords:

anilides, diuretics, 4-methyl-2-oxo-1, 2-dihydroquinoline-3-carboxylic acid, amidation

Abstract

A large series of 4-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid anilides has been prepared as potential diuretic agents. The effect of all of the synthesized compounds on the urinary function of the kidney has been investigated. The appearance of a  "structure – diuretic activity" relationship is discussed.

How to Cite
Ukrainets, I. V.; Bereznyakova, N. L.; Parshikov, V. A.; Naboka, O. I.  Chem. Heterocycl. Compd. 2008, 44, 178. [Khim. Geterotsikl. Soedin. 2008, 239.]

For this article in the English edition see DOI 10.1007/s10593-008-0029-1


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Published

2022-08-10

Issue

No. 2 (2008)

Section

Original Papers