ACYLATION OF PYRROLO[1,2-<i>a</i>]PYRAZINES

Authors

  • В. И. Теренин M. V. Lomonosov Moscow State University, Moscow 119992
  • М. А. Буткевич M. V. Lomonosov Moscow State University, Moscow 119992
  • А. C. Иванов M. V. Lomonosov Moscow State University, Moscow 119992
  • Е. В. Кабанова M. V. Lomonosov Moscow State University, Moscow 119992

DOI:

https://doi.org/10.1007/6983

Keywords:

pyrrolo[1, 2-a]pyrazines, acylation, electrophilic substitution

Abstract

The acylation of pyrrolo[1,2-a]pyrazines with acetic anhydride and the acid chlorides of  various carboxylic  acids has been studied. It has been  shown that pyrrole[1,2-a]pyrazines are selectively acylated at the α-position of the pyrrole ring when it is free. Products of the condensation of 1-methyl-substituted pyrrolo[1,2-a]pyrazines have been obtained for the first time in the process of acetylation.

How to Cite
Terenin, V. I.; Butkevich, M. A.; Ivanov, A. S.; Kabanova, E. V.  Chem. Heterocycl. Compd. 2008, 44, 200. [Khim. Geterotsikl. Soedin. 2008, 263.]

For this article in the English edition see DOI 10.1007/s10593-008-0026-4

 

Published

2022-08-15

Issue

Section

Original Papers