A CONVENIENT METHOD FOR THE SYNTHESIS OF SUBSTITUTED 2-ALKYLTHIO-3-CYANO-4,6-DIMETHYL-5-PHENYLCARBAMOYL-1,4-DIHYDROPYRIDINES

Authors

  • С. Г. Кривоколыско Taras Shevchenko Lugansk State Pedagogical University
  • B. Д. Дяченко Taras Shevchenko Lugansk State Pedagogical University
  • B. П. Литвинов N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

DOI:

https://doi.org/10.1007/71

Keywords:

acetaldehyde, acetoacetaldehyde, substituted 3-cyanopyridin-2(1H)-thione, thieno[2, 3-b]-pyridine, 3-cyano-1, 4-dihydropyridine, cyanothioacetamide, multicomponent condensation

Abstract

Substituted 2-alkylthio-3-cyano-4,6-dimethyl-5-phenylcarbamoyl-1,4-dihydropyridines were obtained by successive reaction of acetaldehyde with cyanothioacetamide and acetoacetanilide, α-chloracetamide or phenacyl bromide in the presence of piperidine.

Authors: S. G. Krivokolysko, V. D. Dyachenko, and V. P. Litvinov.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (3), pp 284-286

http://link.springer.com/article/10.1007/BF02256865

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Published

2012-11-30

Issue

No. 3 (2000)

Section

Original Papers