SYNTHESIS AND INTRAMOLECULAR RECYCLIZATION OF 2,2-DIALKYL-6-CHLORO-4-HYDROXYMETHYLBENZO[<i>f</i>]ISOINDOLINIUM SALTS
DOI:
https://doi.org/10.1007/7492Keywords:
dialkyl(2-butynyl-4-hydroxy)[3-(p-chlorophenyl)propargyl]ammonium salts, 2, 2-dialkyl-6-chloro-4-hydroxymethylbenzo[f]isoindolinium salts, base catalysis, recyclization, cyclizationAbstract
The intramolecular cyclization of dialkyl(2-butynyl-4-hydroxy)[3-(p-chlorophenyl)propargyl]ammonium chlorides, catalyzed by aqueous KOH, was realized. It was shown that the obtained products – 2,2-dialkyl-6-chloro-4-hydroxymethylbenzo[f]isoindolinium chlorides – readily undergo recyclization under the action of a twofold molar amount of KOH in aqueous solution with heating with the formation of 4-dialkylaminomethyl-8-chloro-1,3-dihydronaphtho[1,2-c]furans.How to Cite
Chukhajian, E. O.; Khachatryan, A. A.; Gevorkyan, A. R.; Panosyan, G. A. Chem. Heterocycl. Compd. 2007, 43, 701. [Khim. Geterotsikl. Soedin. 2007, 834.]
For this article in the English edition see DOI 10.1007/s10593-007-0114-x