STUDY OF 5,5-DIALKYL-3-PERFLUOROALKYL-5,6-DIHYDRO-1,2,4-TRIAZOLO[3,4-<i>a</i>]ISOQUINOLINE SYNTHESIS ROUTES
DOI:
https://doi.org/10.1007/78Abstract
Substituted 3-trifluoromethyl-5,6-dihydro-1,2,4-triazolo[3,4-a]isoquinolines were obtained by the reaction of substituted 1-methylthio-3,4-dihydroisoquinolines with hydrazine hydrate and trifluoroacetic acid. The corresponding 3-perfluoroalkyl derivatives are formed in the course of dehydration of 2-(3,3-dimethyl-3,4-dihydro-1-isoquinolyl)hydrazides of perfluorocarboxylic acids.
Authors: V. A. Glushkov, Yu. V. Shklyaev, O. A. Mayorova, G. A. Postanogova, E. V. Feshina.
English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (3), pp 319-325