2-(2-FURYL)IMIDAZO[1,2-<i>a</i>]PYRIMIDINE SYNTHESIS AND ELECTROPHILIC SUBSTITUTION REACTIONS

Authors

  • Н. Салдабол Latvian Institute of Organic Synthesis, Riga LV-1006
  • Ю. Попелис Latvian Institute of Organic Synthesis, Riga LV-1006
  • О. Ландо Latvian Institute of Organic Synthesis, Riga LV-1006
  • В. Славинская Latvian Institute of Organic Synthesis, Riga LV-1006

DOI:

https://doi.org/10.1007/8006

Keywords:

2-(2-furyl)imidazo[1, 2-a]pyrimidine, azocoupling, bromination, nitrosation, sulfonation

Abstract

The synthesis of 2-(2-furyl)imidazo[1,2-a]pyrimidine has been carried out. Azocoupling,  nitrosation, and bromination by 1 mole of bromine occur at position 3 of the bicycle. Reaction with 2 mol of bromine gives the 3,5'-disubstituted derivative. Bromination  using 1 mol of bromine in 40% hydrobromic acid and sulfonation occur initially at the 5' position of the furyl group.

How to Cite
Saldabol, N.; Popelis, J.; Lando, O.; Slavinska, V.  Chem. Heterocycl. Compd. 2006, 42, 495. [Khim. Geterotsikl. Soedin. 2006, 565.]

For this article in the English edition, see DOI 10.1007/s10593-006-0116-0


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Published

2023-08-30

Issue

No. 4 (2006)

Section

Original Papers