SYNTHESIS OF SOME NEW BIOLOGICALLY ACTIVE COUMARIN DERIVATIVES

Authors

  • N. Hamdi Institut National de Recherche et d'Analyse physicochimique, Technopôle de Sidi Thabet 2020
  • C. Lidrissi Dpto. Quimica Fisica, Bioquimica y Quimica Inorganica, Universidad de Almeria, Almeria
  • M. Saoud Dpto. Quimica Fisica, Bioquimica y Quimica Inorganica, Universidad de Almeria, Almeria
  • A. Romerosa Nievas Dpto. Quimica Fisica, Bioquimica y Quimica Inorganica, Universidad de Almeria, Almeria
  • H. Zarrouk Institut National de Recherche et d'Analyse physicochimique, Technopôle de Sidi Thabet 2020

DOI:

https://doi.org/10.1007/8018

Keywords:

benzodiazepin-2-one, 4-hydroxycoumarin, o-phenylenediamine, antibacterial, activity

Abstract

The reaction of 4-hydroxycoumarin in toluene with a variety of aromatic binucleophilic compounds has been studied. 3-(Dimethylaminomethylene)chromane-2,4-dione was used as a key intermediate for the preparation of bis[N-(4-oxocoumarinylmethylene)]-1,4-diamines. Alternative synthetic procedures and antibacterial activity data of some of the new compounds are given.

How to Cite
Hamdi, N.; Lidrissi, C.; Saoud, M.; Nievas, A. R.; Zarrouk, H.  Chem. Heterocycl. Compd. 2006, 42, 320. [Khim. Geterotsikl. Soedin. 2006, 361.]

For this article in the English edition, see DOI 10.1007/s10593-006-0088-0

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Published

2023-08-31

Issue

No. 3 (2006)

Section

Original Papers