REACTION OF 2-AMINOTHIOPHENOL WITH ACRYLIC ACID AND CONVERSION OF THE RESULTANT ADDUCTS
DOI:
https://doi.org/10.1007/8063Keywords:
acrylic acid, β-alanine, 2-aminothiophenol, hydrobenzothiazepinone, disulfide, mercaptobenzothiazole, phenyldihydropyrimidinonethioneAbstract
The reaction of acrylic acid with 2-aminothiophenol gives 5-carboxyethyl-2,3-dihydro-5H-benzo[b][1,4]-thiazepin-4-one and N-[2-(carboxyethylthio)phenyl]-β-alanine, while the reaction of acrylic acid with bis(2-aminophenyl) disulfide gives bis[2-(carboxyethylamino)phenyl] disulfide. The action of potassium thiocyanate in acid medium on the carboxyethylamino derivatives yields 1-[2-carboxyethylthio)phenyl]dihydro-4(1H,3H)-pyrimidinone-2-thione, bis-{2-[dihydro-4(1H,3H)-pyrimidinone-2-thion-1-yl]phenyl} disulfide, and 3-(2-mercaptobenzothiazol-3-yl)propanoic acid.
How to Cite
Rutkauskas, K.; Beresnevicius, Z.-I. Chem. Heterocycl. Compd. 2006, 42, 227. [Khim. Geterotsikl. Soedin. 2006, 256.]
For this article in the English edition, see DOI 10.1007/s10593-006-0076-4
