3-ACETYL-4-METHYLPYRIDO[2,1-<i>a</i>]ISOQUINOLIN-2-ONES. [2+4] CYCLOCONDENSATION OF 3,4-DIHYDROISOQUINOLINES WITH TRIACETYLMETHANE

Authors

  • О. В. Гулякевич State Science Establishment, Institute of Bioorganic Chemistry, Belarus National Academy of Sciences, Minsk 220141
  • П. В. Курман RTSC "Ecomir", Belorussian Republic Academy of Sciences, Minsk 220012
  • А. С. Ляхов F. Skorina Science Research Center, Belorussian State University, Minsk 220050
  • А. Л. Михальчук State Science Establishment, Institute of Bioorganic Chemistry, Belarus National Academy of Sciences, Minsk 220141

DOI:

https://doi.org/10.1007/8084

Keywords:

azomethines, benzo[a]quinolizines, 3, 4-dihydroisoquinolines, Schiff's base, pyrido[2, 1-a]isoquinolines, triacetylmethane, annelation, [2 4] cyclocondensation

Abstract

Treatment of 3,4-dihydroisoquinolines with triacetylmethane  in  refluxing  alcohol for 2-3 h gave 3-acetyl-4-methylpyrido[2,1-a]isoquinolin-2-ones. Their  basic physicochemical properties have been studied.

How to Cite
Gulyakevich, O. V.; Kurman, P. V.; Lyakhov, A. S.; Mikhal'chuk, A. L.  Chem. Heterocycl. Compd. 2006, 42, 70. [Khim. Geterotsikl. Soedin. 2006, 77.]

For this article in the English edition, see DOI 10.1007/s10593-006-0049-7


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Published

2023-09-20

Issue

No. 1 (2006)

Section

Original Papers