SYNTHESES BASED ON 8-SUBSTITUTED 3-BROMOACETYL-3,8-DIMETHYL-2,7-DIOXASPIRO[4,4]NONANE-1,6-DIONES

Authors

  • Т. В. Кочикян Yerevan State University, Chemistry Department, Yerevan 375025
  • Э. В. Арутюнян Yerevan State University, Chemistry Department, Yerevan 375025
  • В. С. Арутюнян Yerevan State University, Chemistry Department, Yerevan 375025
  • А. А. Аветисян Yerevan State University, Chemistry Department, Yerevan 375025

DOI:

https://doi.org/10.1007/8090

Keywords:

aminothiazoles, bromoacetyl lactones, spirodibutanolides, triazoles

Abstract

By reaction of 8-substituted 3-bromoacetyl-3,8-dimethyl-2,7-dioxaspiro[4,4]nonane-1,6-diones with thiourea and substituted thioureas under Hansch  reaction conditions, we have obtained the novel heterocycles 3-[2'-amino(arylamino)thiazol-4-yl]-3,8-dimethyl-2,7-dioxaspiro[4,4]nonane-1,6-diones. By reacting the above-indicated bromoacetyl spirodilactones with 5-aryl-3-mercapto-1,2,4-triazoles, we obtained 8-substituted 3-(aryl-3,8-dimethyl-1',2',4'-triazol-3'-yl)thioacetyl-2,7-dioxaspiro[4,4]nonane-1,6-diones.

How to Cite
Kochikyan, T. V.; Harutyunyan, E. V.; Harutyunyan, V. S.; Avetisyan, A. A.  Chem. Heterocycl. Compd. 2006, 42, 109. [Khim. Geterotsikl. Soedin. 2006, 123.]

For this article in the English edition, see DOI 10.1007/s10593-006-0054-x


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Published

2023-09-22

Issue

No. 1 (2006)

Section

Original Papers