SYNTHESIS OF 1-ARYL-4-AZOLYLBUTANONES

Authors

  • Д. А. Карачёв D. I. Mendeleev University of Chemical Technology of Russia, Moscow
  • С. В. Попков D. I. Mendeleev University of Chemical Technology of Russia, Moscow

DOI:

https://doi.org/10.1007/8212

Keywords:

1-aryl-4-azolyl-1-butanones, dioxolanes, p-substituted γ-chlorobutyrophenones, imidazole, ketals, 1, 2, 4-triazole, alkylation of azoles

Abstract

A convenient method was developed for the synthesis of substituted 4-azolyl-1-arylbutanones from the available  γ-chlorobutyrophenones by successive stages of transformation into ketals, alkylation of sodium imidazolate or 1,2,4-triazolate by the ketals in DMF, and removal of the ketal protection.

How to Cite
Karachev, D. A.; Popkov, S. V.  Chem. Heterocycl. Compd. 2005, 41, 987. [Khim. Geterotsikl. Soedin. 2005, 1161.]

For this article in the English edition, see DOI 10.1007/s10593-005-0265-6

 

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Published

2023-10-27

Issue

No. 8 (2005)

Section

Original Papers